My full CV can be downloaded here.

Education

• B.S. in Nutritional Science, Iowa State University, 2012
• M.S. in Pathology, University of Iowa, 2014
• Ph.D. in Cancer Biology, University of Iowa, 2020
• M.D. at the University of Iowa, 2020

Invited Presentations

• Single-cell mRNA sequencing of murine and human alopecia areata identifies immune cell profiles predictive of human disease state. (2020, June). Virtually presented at the Academy of Clinical Laboratory Physicians and Scientists Annual Meeting in Iowa City, IA
• Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression. (2019, May). Presented at the Society for Investigative Dermatology Annual Meeting in Chicago, Illinois.
• Transcriptional Heterogeneity in cancer-associated regulatory T cells is predictive of survival. Presented at the Single-Cell RNA sequencing Symposium by the Iowa Institute of Genetics, Iowa City, Iowa.
• Paracrine Regulation of Breast Cancer Tumorigenesis. (2016, April). Presented at the Midwestern Association of Graduate Schools Annual Conference in Chicago, Illinois.

National or Regional Abstracts

• Borcherding, N., Crotts, S., Ortolan, L., Bormann, N., & Jabbari, A. (2020, June). Single-cell mRNA sequencing of murine and human alopecia areata identifies immune cell profiles predictive of human disease state. Presented at the Academy of Clinical Laboratory Physicians and Scientists Annual Meeting in Iowa City, IA
• Renavikar, P., Sinha, S., Brate, A., Crawford, M., Borcherding, N., Steward, S. & Karandikar, N. (2020, May). Immune suppressive deficit in human Tc1 cells secondary to IL-12-induced pathways. Presented at the Academy of Clinical Laboratory Physicians and Scientists Annual Meeting in Iowa City, IA
• Hoffmann, D., Feagle, T., & Borcherding, N. (2020, April). Virtual Anatomy Videos for Pre-Lab Preparation: Does Usage Correlate with Grade Outcomes. Accepted to Experimental Biology Annual Meeting in San Diego, CA. (Canceled due to COVID-19).
• Cole, K., Councilman, K., Zhang, W., & Borcherding N. (2020, March). WNT/β-Catenin Signaling Correlates with Improved Survival in Luminal A Breast Cancer. Presented at the USCAP Annual Meeting in Los Angeles, CA.
• Borcherding, N., Voigt, A., Liu, V., Link, B.K., Zhang, W., & Jabbari, A. (2019, May) Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression. Presented at the Society for Investigative Dermatology Annual Meeting in Chicago, Il.
• Borcherding, N., Bormann, N., Zhang, W. (2018, January). Using data analytics to predict and improve cancer immunotherapy response. Presented at the American Physician Scientist Association Midwest Regional Meeting in Iowa City, IA.
• Borcherding, N., Jo, S., Zhang, W. (2017, October). Targeting mismatch repair for basal-like breast cancer. Presented at the Cancer Biology Training Consortium Annual Meeting in Portland, OR.
• Feagle, T., Borcherding, N., Hoffmann, D. Students Prefer 3D Anatomy Videos for Prelab Preparation Compared to Traditional Resources and Usage is Related to Class Performance. Presented at the annual Experimental Biology Conference in Chicago, IL.
• Kolb, R., Kluz, P., Wei, T.Z., Bormann, N., Borcherding, N., Markan, K., Pothoff, B., Tan, N.S., Sutterwala, F., & Zhang W. (2017, February). IL-1beta promotes obesity-driven breast cancer progression through the upregulation of Angptl4 in adipocytes. Presented at Inflammation-driven Cancer: Mechanisms to Therapy Keystone Symposia in Keystone, CO.
• Schaefer, K.A., Toral, M., Velez, G., Cox, A., Baker, S., Borcherding, N., Colgan, D.F., Smits, M.M., Bondada, V., Mashburn, C.B., Yu, C., Geddes, J., Tsang, S.H., Bassuk, A.G., Mahajan, V.B. (2016, June). Calpain-5 expression in the retina localizes to photoreceptor synapses. Presented at the FASEB Conference for The Biology of Calpains in Health and Disease in Big Sky, MT.
• Kolb, R., Phan, L., Borcherding, N., Liu, Y., Yuan, F., Janowski, A.M., Xie, Q., Markanm K., Li, W., Potthoff, M., Fuentes-Mattei, E., Ellies, L., Knudson, M., Lee, M., Yeung, S., Cassel, S., Sutterwala, F., & Zhang, W. (2016, January). Obesity-induced Nlrc4 inflammasome promote angiogenesis in breast cancer. Presented at the AACR Special Conference: The Function of Tumor Microenvironment in Cancer in San Diego, CA.
• Kolb, R., Borcherding, N., Liu, Y., Yuan, F., Xie, Q., Sutterwala, F., Zhang, W. (2015, April). NLRC4 inflammasome promotes breast cancer progression in diet-induced obese mice. Presented at the American Association for Cancer Research Annual Meeting in Philadelphia, PA.
• Borcherding, N., Kusner, D., Kolb, R., Xie, Q., Zhang, W. (2015, April). Paracrine Wnt5a signaling inhibits the expansion of tumor inititating cells via Ryk/TGFβR/Smad2. Presented at the ASCI/AAP/APSA Annual Joint Meeting in Chicago, IL.
• Borcherding, N., Kusner, D., Kolb, R., Xie, Q., Zhang, W. (2014, April). Wnt5a/ROR1 Axis in Triple Negative Breast Cancer Progression and Potential Therapy. Presented at the American Association for Cancer Research Annual Meeting in San Diego, CA.
• Kolb, R., Liu, Y., Xie, Q., Borcherding, N., Li, W., Zhang, W. (2014, April). Inflammasome activation in obesity-associated breast cancer progression. Presented at the American Association for Cancer Research Annual Meeting in San Diego, CA.
• Xie, Q., Borcherding, N., Kolb, R., Zhang, W. (2014, April). CD177, A novel Metastasis Suppressor of Breast Cancer. Presented at the American Association for Cancer Research Meeting, San Diego, CA.

Funding

• 2017-20 NIH F30 CA206255 (PI), The role of paracrine WNT5A/RYK in ErbB2-driven tumorigenesis. $151,150
• 2017-18 Oberley Seed Grant for Experiment Therapeutics (co-PI), Targeting mismatch repair for immunotherapy in basal-like breast cancer. $20,000
• 2015-16 American Medical Association Foundation Research Seed Grant (PI), Paracrine non-canonical Wnt signaling in breast cancer. $4,895

Awards and Recognitions

• 2020 William L. Roberts Young Investigator Award with Distinction, Academy of Clinical and Laboratory Physicians and Scientists
• 2020 Special Achievement in Pathology, Iowa Pathology Society
• 2019 Alpha Omega Alpha Honor Medical Society Induction
• 2018 Graduate Research Excellence Award in Biological Sciences Finalist, University of Iowa
• 2018 Hancher-Finkbine Medallion, University of Iowa
• 2017 Richard G. Lynch, MD Award for Pathology, University of Iowa
• 2015 Distinguished Thesis Award, Midwestern Association of Graduate Schools
• 2015 L.B. Sims Outstanding Master’s Thesis Award in Biological Sciences, University of Iowa
• 2015 Richard G. Lynch, MD Award for Pathology, University of Iowa
• 2014 Richard G. Lynch, MD Award for Pathology, University of Iowa
• 2012 University Graduation Marshall, Iowa State University
• 2012 Graduate Summa Cum Laude, Iowa State University
• 2012 Departmental Scholarly Achievement Award, Iowa State University
• 2005 Eagle Scout Award, Boy Scouts of America